DAI Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | DAI |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | n/a |
| Isotype | n/a |
| Format | unconjugated |
| Size | 0.05 mg |
| Concentration | IgG concentration 1.0mg/ml |
| Applications | ELISA (EIA), Immunohistology Paraffin*, Western Blot (WB)* |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This product recognizes human DAI, also known as Z-DNA Binding Protein (ZBP1), a 46kDa DNA binding protein belonging to a family of proteins that contain a Za domain which specifically binds to the left-handed Z-DNA and Z-RNA. . . Initial studies suggested that DAI may be involved in processes such host response to neoplasia. Additional research has indicated that the cytosolic DAI can act like the toll-like receptor TLR9 by detecting cytosolic double-stranded (ds) DNA and trigger induction of type I interferon and other innate immune responses. It is thought that the binding of DAI to dsDNA enhances its association with innate immune response proteins such as the IRF3 transcription factor and the serine/threonine kinase TBK1 (also known |
| Immunogen | Immunogen: Synthetic peptide corresponding to an 18 amino acid sequence from near the carboxy terminus of human ZBP1. Buffer Solution: Phosphate buffered saline Antiserum Preparation: Antisera to human DAI were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG prepared from whole serum by affinity chromatography. Target Species: Human |
| Other Names | [Z-DNA-binding protein 1 isoform b; Z-DNA-binding protein 1; Z-DNA-binding protein 1; DNA-dependent activator of IFN-regulatory factors; DNA-dependent activator of IRFs; DNA-dependent activator of interferon regulatory factors; tumor stroma and activated macrophage protein DLM-1; Z-DNA binding protein 1; Tumor stroma and activated macrophage protein DLM-1], [ZBP1; ZBP1; DAI; DLM1; DLM-1; C20orf183; C20orf183; DLM1] |
| Gene, Accession # | [DAI], Gene ID: 81030, NCBI: NP_001153889.1, UniProt: Q9H171 |
| Catalog # | MBS223548 |
| Price | $235 |
| Order / More Info | DAI Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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