Edit |   |
---|---|
Antigenic Specificity | CCDC88A |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.02 mL, 0.06 mL, 0.12 mL |
Concentration | 2.7mg/mL |
Applications | ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes a member of the Girdin family of coiled-coil domain containing proteins. The encoded protein is an actin-binding protein that is activated by the serine/threonine kinase Akt and plays a role in cytoskeleton remodeling and cell migration. The encoded protein also enhances Akt signaling by mediating phosphoinositide 3-kinase (PI3K)-dependent activation of Akt by growth factor receptor tyrosine kinases and G protein-coupled receptors. Increased expression of this gene and phosphorylation of the encoded protein may play a role in cancer metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
Immunogen | Immunogen: Synthetic peptide of human CCDC88A |
Other Names | [APE; GIV; GRDN; HkRP1; GIRDIN; KIAA1212] |
Gene, Accession # | [CCDC88A], Gene ID: 55704, NCBI: AAI44321.1 |
Catalog # | MBS2520493 |
Price | $110, $150, $225 |
Order / More Info | CCDC88A Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |