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Antigenic Specificity | C3aR, Rat |
Clone | 74 |
Host Species | Mouse |
Reactive Species | rat |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | F, Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Product Description: The monoclonal antibody 74 reacts with the rat receptor for C3a. The monoclonal antibody 74 is in the literature also referred to as clone rC3aRZ1. In the course of complement activation the C3a receptor functions as the cell surface receptor for the anaphylatoxin C3a, the C-terminal 77 amino acid cleavage product of the alpha chain of C3, but not for C3a-desArg. All cellular responses to C3a are specifically mediated by interactions with the membrane bound C3a receptor, a seven transmembrane GTP-binding-protein-coupled receptor that belongs to the rhodopsin supergene family. The 54 kDa C3a receptor is widely distributed in myeloid cells, peripheral tissues and the central nervous system. Expression of C3aR has been dem |
Immunogen | n/a |
Other Names | n/a |
Gene, Accession # | [C3aR] |
Catalog # | MBS584414 |
Price | $665 |
Order / More Info | C3aR, Rat Antibody from MYBIOSOURCE INC. |
Product Specific References | Luhmann, A et al; Immunohistochemical analysis of human and rat C3a receptor expression by the use of monoclonal antibodies. Mol Immunol 2001, 38: 108 |