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Antigenic Specificity | IFNA1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of total IFNA1 protein. Interferon-a1 is a member of the Type I IFN (1) family best known for their antiviral activity. Most nucleated cells produce one or more Type I IFNs in response to viral infection (2). Secreted Type I IFN then induces viral protective responses in neighboring non-infected cells. Type I IFNs also enhance virus-induced apoptosis (3). Other IFNA11 activities include enhancement of dendritic cell maturation and cytotoxic T cell activity (4). IFNA11 binds to the IFNA1R1 and IFNA1R2 heterodimer (1). Intracellular signaling through the Jak/Stat pathway is best characterized (3). However, the PI3K, ERK, and p38 kinase pathways are also involved (5). The antiviral activities of the IFNs h |
Immunogen | Immunogen Type: Recombinant Protein Immunogen Description: Recombinant protein of human IFNA1. |
Other Names | [IFNA1; IFL; IFN; IFN-ALPHA; IFNA13] |
Gene, Accession # | [IFNA1], Gene ID: 3447, NCBI: NP_008831.3, UniProt: P01562 |
Catalog # | MBS9401760 |
Price | $255 |
Order / More Info | IFNA1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |