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Antigenic Specificity | MYSM1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: MYSM1 Polyclonal Antibody detects endogenous levels of MYSM1 protein. MYSM1 (Myb Like, SWIRM And MPN Domains 1) is a Protein Coding gene. Metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. Acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR)-induced gene activation. Diseases associated with MYSM1 include hemorrhagic cystitis. Gene Ontology (GO) annotatio |
Immunogen | Immunogen: Synthesized peptide derived from the internal region of human MYSM1 at AA range: 490-570 |
Other Names | [Rabbit MYSM1; MYSM1; KIAA1915; Histone H2A deubiquitinase MYSM1; 2A-DUB; Myb-like; SWIRM and MPN domain-containing protein 1] |
Gene, Accession # | [MYSM1], Gene ID: 114803, NCBI: NP_001078956.1, UniProt: Q5VVJ2 |
Catalog # | MBS9702574 |
Price | $130, $220, $325 |
Order / More Info | MYSM1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |