Edit |   |
---|---|
Antigenic Specificity | MMP-1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.03 mg, 0.1 mg |
Concentration | 0.5 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Background: Matrix metalloproteinases (MMPs) are zinc-dependent endopeptidases that degrade substances within the extracellular matrix. The MMP family includes six different groups of enzymes: collagenases, gelatinases, stromelysins, transmembrane MMPs, matrilysins and others. MMPs are secreted as proenzymes that have to be cleaved in order to be activated. Other MMPs, plasmins as well as other factors activate MMPs. MMPs are thomught to play an important role in tissue remodeling associated with various physiological and pathological processes. MMP1 cleaves collagens of types I, II, III, VII and X. MMP1 is thomught to play an important role in rheumatoid and osteo-arthritis pathogenesis as mediators of cartilage and bone destruction. |
Immunogen | Immunogen: E. coli-expressed recombinant human MMP-1. Positive Control: Recombinant human MMP-1 |
Other Names | [CLG; CLGN; Fibroblast collagenase; Interstitial collagenase; MMP-1], [APICBIBUN_04585] |
Gene, Accession # | [MMP-1], NCBI: CDH42639.1, UniProt: U4P0U0 |
Catalog # | MBS840481 |
Price | $150, $290 |
Order / More Info | MMP-1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |