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Antigenic Specificity | Macrophage inhibitory cytokine-1 (MIC-1) |
Clone | [9E99] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | Protein G purified |
Size | 0.05 mg, 0.1 mg |
Concentration | 2mg/ml |
Applications | ELISA (EL/EIA), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes native human Macrophage inhibitory cytokine-1. Macrophage inhibitory cytokine-1 (MIC-1) is a member of the transforming growth factor-beta superfamily that regulates a wide variety of physiological processes involved in tissue differentiation and maintenance (1). MIC-1 is synthesized as a 62kD intracellular protein, which, after cleavage by a furin like protease, is secreted as a 25kD disulphide-linked dimeric protein. Expression of MIC-1 results in inhibition of macrophage activation, regulated by the p53 pathway, in response to pro-inflammatory monokines (1,2). MIC-1 is involved in tumor pathogenesis and its measurement can be used as a clinical tool for the diagnosis of a wide range of cancers. It could be a useful marker for |
Immunogen | Immunogen: cDNA encoding aa30-194 from the N-terminal of human MIC-1 proprotein. |
Other Names | [-Macrophage inhibitory cytokine-1 (MIC-1)], [GDF15; GDF15; PDF; MIC1; PLAB; MIC-1; NAG-1; PTGFB; GDF-15; GDF15; MIC1; PDF; PLAB; PTGFB] |
Gene, Accession # | Gene ID: 9518, UniProt: Q99988 |
Catalog # | MBS605694 |
Price | $460, $640 |
Order / More Info | Macrophage inhibitory cytokine-1 (MIC-1) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |