Edit |   |
---|---|
Antigenic Specificity | BCL-XL (Ab-62) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | epitope affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of total BCL-XL protein. Potent inhibitor of cell death. Isoform Bcl-X(L) anti-apoptotic activity is inhibited by association with SIVA isoform 1. Inhibits activation of caspases By similarity. Appears to regulate cell death by blocking the voltage-dependent anion channnel (VDAC) by binding to it and preventing the release of the caspase activator, cytochrome c, from the mitochondrial membrane. The Bcl-X(S) isoform promotes apoptosis. |
Immunogen | Immunogen Type: Peptide-KLH Immunogen Description: Peptide sequence around aa.60~64 (A-D-S-P-A) derived from human BCL-XL. |
Other Names | [Apoptosis regulator Bcl-X] |
Gene, Accession # | [BCL-XL], Gene ID: 598, NCBI: NP_001182.1, UniProt: Q07817 |
Catalog # | MBS9403603 |
Price | $200, $255 |
Order / More Info | BCL-XL (Ab-62) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |