BCL-XL (Ab-62) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityBCL-XL (Ab-62)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatepitope affinity purified
Size0.05 mL, 0.1 mL
Concentration1.0 mg/ml
ApplicationsWestern Blot (WB)
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DescriptionThe antibody detects endogenous level of total BCL-XL protein. Potent inhibitor of cell death. Isoform Bcl-X(L) anti-apoptotic activity is inhibited by association with SIVA isoform 1. Inhibits activation of caspases By similarity. Appears to regulate cell death by blocking the voltage-dependent anion channnel (VDAC) by binding to it and preventing the release of the caspase activator, cytochrome c, from the mitochondrial membrane. The Bcl-X(S) isoform promotes apoptosis.
ImmunogenImmunogen Type: Peptide-KLH Immunogen Description: Peptide sequence around aa.60~64 (A-D-S-P-A) derived from human BCL-XL.
Other Names[Apoptosis regulator Bcl-X]
Gene, Accession #[BCL-XL], Gene ID: 598, NCBI: NP_001182.1, UniProt: Q07817
Catalog #MBS9403603
Price$200, $255
Order / More InfoBCL-XL (Ab-62) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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