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Antigenic Specificity | Human Flt-3 Ligand |
Clone | [9G23] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | Protein G purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Neutralization |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Flt-3 Ligand, also known as FL, is an alpha-helical cytokine that promotes the differentiation of multiple hematopoietic cell lineages. Mature human Flt-3 Ligand consists of a 158 amino acid (aa) extracellular domain (ECD) with a cytokine-like domain and a juxtamembrane region, a 21 aa transmembrane segment, and a 30 aa cytoplasmic tail. Within the ECD, human Flt-3 Ligand shares 71% and 65% aa sequence identity with mouse and rat Flt-3 Ligand, respectively. Human and mouse Flt-3 Ligand show cross-species activity. Flt-3 Ligand is expressed as a non-covalentlylinked dimer by T cells and bone marrow and thymic fibroblasts. Each 36 kDa chain carries approximately 12 kDa of N- and O-linked carbohydrates. Alternate splicing and proteolytic cleav |
Immunogen | Antibody Generation: This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human recombinant protein of Flt-3 ligand. Antigen: Recombinant human Flt-3 ligand. Reconstitution buffer: PBS (Sterile). mRNA RefSeq: NM_004119 |
Other Names | [FLT3LG; FL; FLT3L], [FLT3; FLT3; FLK2; STK1; CD135; FLK-2; CD135; FLK2; STK1; FLK-2; FLT-3; STK-1] |
Gene, Accession # | [Flt-3 Ligand], Gene ID: 2322, NCBI: NP_004110.2, UniProt: P36888 |
Catalog # | MBS690558 |
Price | $490 |
Order / More Info | Human Flt-3 Ligand Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |