MAPKAP1 - middle region Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | MAPKAP1 - middle region |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | mouse |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Subunit of mTORC2, which regulates cell growth and survival in response to hormonal signals. mTORC2 is activated by growth factors, but, in contrast to mTORC1, seems to be nutrient-insensitive. mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors. mTORC2 promotes the serum-induced formation of stress-fibers or F-actin. mTORC2 plays a critical role in AKT1 'Ser-473' phosphorylation, which may facilitate the phosphorylation of the activation loop of AKT1 on 'Thr-308' by PDK1 which is a prerequisite for full activation. mTORC2 regulates the phosphorylation of SGK1 at 'Ser-422'. mTORC2 also modulates the phosphorylation of PRKCA on 'S |
| Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the middle region of mouse MAPKAP1 |
| Other Names | [target of rapamycin complex 2 subunit MAPKAP1 isoform a; Target of rapamycin complex 2 subunit MAPKAP1; target of rapamycin complex 2 subunit MAPKAP1; mitogen-activated protein kinase associated protein 1; Mitogen-activated protein kinase 2-associated protein 1; Stress-activated map kinase-interacting protein 1; SAPK-interacting protein 1] |
| Gene, Accession # | [MAPKAP1], Gene ID: 227743, NCBI: NP_001277554.1, UniProt: Q8BKH7 |
| Catalog # | MBS3224152 |
| Price | $335 |
| Order / More Info | MAPKAP1 - middle region Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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