KIAA1967 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | KIAA1967 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: KIAA1967 antibody detects endogenous levels of total KIAA1967. Function: Core component of the DBIRD complex, a multiprotein complex that acts at the interface between core mRNP particles and RNA polymerase II (RNAPII) and integrates transcript elongation with the regulation of alternative splicing: the DBIRD complex affects local transcript elongation rates and alternative splicing of a large set of exons embedded in (A + T)-rich DNA regions. Inhibits SIRT1 deacetylase activity leading to increasing levels of p53/TP53 acetylation and p53-mediated apoptosis. Inhibits SUV39H1 methyltransferase activity. As part of a histone H3-specific methyltransferase complex may mediate ligand-dependent transcriptional activation by nuclear h |
| Immunogen | Immunogen: A synthesized peptide Subcellular Location: Nucleus. Tissue Specificity: Expressed in gastric carcinoma tissue and the expression gradually increases with the progression of the carcinoma (at protein level). Expressed ubiquitously in normal tissues. Expressed in 84 to 100% of neoplastic breast, lung, and colon tissues. Predicted Cross Reactivity: Horse Similarity: Horse (86%) |
| Other Names | [CCAR2; Cell cycle and apoptosis regulator 2; Cell division cycle and apoptosis regulator protein 2; DBC-1; DBC.1; DBC1; DBIRD complex subunit KIAA1967; Deleted in breast cancer 1; Deleted in breast cancer gene 1 protein; K1967_HUMAN; KIAA1967; NET35; p30 DBC; p30 DBC protein; p30DBC] |
| Gene, Accession # | [KIAA1967], Gene ID: 57805, NCBI: NP_066997.3, UniProt: Q8N163 |
| Catalog # | MBS9604809 |
| Price | $240, $280 |
| Order / More Info | KIAA1967 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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