Edit |   |
---|---|
Antigenic Specificity | ZKSCAN3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: ZKSCAN3 antibody detects endogenous levels of total ZKSCAN3. Function: Transcriptional factor that binds to the consensus sequence 5'-[GT][AG][AGT]GGGG-3' and acts as a repressor of autophagy. Specifically represses expression of genes involved in autophagy and lysosome biogenesis/function such as MAP1LC3B, ULK1 or WIPI2. Associates with chromatin at the ITGB4 and VEGF promoters. Also acts as a transcription activator and promotes cancer cell progression and/or migration in various tumors and myelomas.Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family. |
Immunogen | Immunogen: A synthesized peptide derived from human ZKSCAN3 Subcellular Location: Nucleus. Tissue Specificity: Overexpressed in various tumors, such as multiple myeloma, colorectal and prostate cancers (at protein level). |
Other Names | [dJ874C20.1; mszf35; SCAN-KRAB-zinc finger protein; Skz1; Zf47; Zfp-47; ZFP306; Zfp307; Zfp47; Zinc finger and SCAN domain containing protein 13; Zinc finger and SCAN domain-containing protein 13; Zinc finger protein 306; Zinc finger protein 306, isoform CRA_a; Zinc finger protein 307; Zinc finger protein 309; Zinc finger protein 47 homolog; Zinc finger protein with KRAB and SCAN domains 3; Zinc finger protein with KRAB and SCAN domains 3; Zinc finger protein zfp47; Zinc finger with KRAB and SCAN domains 3; ZKSC3_HUMAN; ZKSCAN3; ZNF309; ZSCAN13; ZSCAN35] |
Gene, Accession # | [ZKSCAN3], Gene ID: 80317, NCBI: NP_001229823.1, UniProt: Q9BRR0 |
Catalog # | MBS9608329 |
Price | $240, $280 |
Order / More Info | ZKSCAN3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |