Beclin2 Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | Beclin2 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | n/a |
| Isotype | n/a |
| Format | unconjugated |
| Size | 0.1 mg |
| Concentration | 1mg/ml |
| Applications | Immunoblotting (IB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This antibody recognizes human and rat Beclin 2. Autophagy is a catabolic process that results in the degradation of bulk cytoplasmic contents within autophagosomes and lysosomes. Beclin 2 is an Atg6/Beclin family member that functions in two distinct lysosomal degradation pathways, autophagy and the downregulation of certain seven- transmembrane-spanning GPCRs. Its role in GPCR lysosomal degradation does not involve Beclin 1 or other Beclin 1/2-interacting proteins such as ATG14 and VPS34 that function in autophagy. Its role in lysosomal degradation also appears to differ from other autophagy- independent functions previously described for yeast Atg6/Vps30 or mammalian Beclin 1, such as vacuolar protein sorting and EGFR degradation. |
| Immunogen | Antigen: Synthetic peptide corresponding to mid-protein amino acids of human Beclin 2. |
| Other Names | [beclin-2; Beclin-2; beclin-2; beclin 2; Beclin-1 autophagy-related pseudogene 1], [BECN2; BECN2; BECN1L1; BECN1P1] |
| Gene, Accession # | Gene ID: 441925, NCBI: NP_001277622.1, UniProt: A8MW95 |
| Catalog # | MBS191011 |
| Price | $410 |
| Order / More Info | Beclin2 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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