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Antigenic Specificity | CHRNA4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | 1.2 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total CHRNA4 protein. This gene encodes a nicotinic acetylcholine receptor, which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses. These pentameric receptors can bind acetylcholine, which causes an extensive change in conformation that leads to the opening of an ion-conducting channel across the plasma membrane. This protein is an integral membrane receptor subunit that can interact with either nAChR beta-2 or nAChR beta-4 to form a functional receptor. Mutations in this gene cause nocturnal frontal lobe epilepsy type 1. |
Immunogen | Immunogen Type: Recombinant Protein Immunogen Description: Fusion protein corresponding to a region derived from internal residues of human cholinergic receptor, nicotinic, alpha 4 (neuronal) |
Other Names | [EBN; BFNC; EBN1; NACHR; NACRA4; NACHRA4] |
Gene, Accession # | [CHRNA4], Gene ID: 1137, NCBI: NP_000735.1, UniProt: P43681 |
Catalog # | MBS9405519 |
Price | $255 |
Order / More Info | CHRNA4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |