ANKRD27 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityANKRD27
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatantigen affinity purified
Size0.02 mL, 0.06 mL, 0.12 mL
Concentration0.5mg/mL
ApplicationsImmunohistochemistry (IHC), ELISA (EIA)
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DescriptionMay be a guanine exchange factor (GEF) for Rab21, Rab32 and Rab38 and regulate endosome dynamics (PubMed:16525121, PubMed:18477474). May regulate the participation of VAMP7 in membrane fusion events; in vitro inhibits VAMP7-mediated SNARE complex formation by trapping VAMP7 in a closed, fusogenically inactive conformation (PubMed:23104059). Involved in peripheral melanosomal distribution of TYRP1 in melanocytes; the function, which probably is implicating vesicle-trafficking, includes cooperation with Rab32, Rab38 and VAMP7 (By similarity). Involved in the regulation of neurite growth; the function seems to require its GEF activity, probably towards Rab21, and VAMP7 but not Rab32/38 (By similarity). Proposed to be involved in Golgi sorting
ImmunogenImmunogen: Fusion protein of human ANKRD27
Other Names[AA408090; Ankrd27; Ankyrin repeat domain 27 (VPS9 domain); Ankyrin repeat domain-containing protein 27; ANR27; BC016493; D330003H11Rik; DKFZp434L0718; FLJ00040; MGC25907; PP12899; VPS9 ankyrin repeat protein; VPS9 domain-containing protein]
Gene, Accession #[ANKRD27], Gene ID: 84079, NCBI: NP_115515, UniProt: Q96NW4
Catalog #MBS2560377
Price$110, $150, $225
Order / More InfoANKRD27 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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