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Antigenic Specificity | TCR, alpha, beta |
Clone | [3H2918] |
Host Species | Mouse |
Reactive Species | cynomolgus monkey |
Isotype | IgG1 |
Format | fluorescein (FITC) conjugate |
Size | 0.1 mg |
Concentration | 0.1mg/ml |
Applications | Flow Cytometry (FC/FACS). Other applications not tested. |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes rat TCR, alpha, beta. Detects a T cell specific molecule consisting of two disulphide-linked subunits of 40 and 46kD molecular weight, respectively, on 97% of peripheral rat T cells as defined by the OX-52 marker. 3H2918 is mitogenic for unseparated spleen cells and for purified T cells. In the rat thymus, mature medullary cells express the 3H2918 determinant at the same level as peripheral T cells, whereas 94% of CD4- CD8- thymocytes are 3H2918 negative. It is most likely directed at a constant determinant of the rat alpha/beta heterodimeric T cell antigen receptor. The T Cell Receptor alpha/beta (TCR) is expressed on T lymphocytes of all mouse strains tested. Plate-bound or soluble antibody activates a/b TCR-bearing T cells. In |
Immunogen | Immunogen: Rat T Blasts and Erythrocytes. Hybridoma: Spleen cells from immunized BALB/c mice were fused with cells of the X63.Ag8.653 mouse myeloma cell line. |
Other Names | TCR, alpha, beta (T Cell Receptor, T-cell Receptor beta-1 Chain C Region, TRBC1, T-cell Receptor alpha Chain C Region, TRAC, TCRA) |
Gene, Accession # | NCBI: AAA61095.1 |
Catalog # | MBS609897 |
Price | $590 |
Order / More Info | TCR, alpha, beta Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |