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Antigenic Specificity | Phospho-MAP4K1 (Y381) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.31 |
Applications | Dot Blot (DB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This MAP4K1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y381 of human MAP4K1. The c-Jun amino-terminal kinases (JNKs)/stress-activated protein kinases (SAPKs) play a crucial role in stress responses in mammalian cells. The mechanism underlying this pathway in the hematopoietic system is unclear, but it is a key in understanding the molecular basis of blood cell differentiation. We have cloned a novel protein kinase, termed hematopoietic progenitor kinase 1 (HPK1), that is expressed predominantly in hematopoietic cells, including early progenitor cells. HPK1 is related distantly to the p21(Cdc42/Rac1)-activated kinase (PAK) and yeast STE20 implic |
Immunogen | n/a |
Other Names | [Mitogen-activated protein kinase kinase kinase kinase 1; Hematopoietic progenitor kinase; MAPK/ERK kinase kinase kinase 1; MEK kinase kinase 1; MEKKK 1; MAP4K1; HPK1] |
Gene, Accession # | [MAP4K1], Gene ID: 11184, NCBI: NP_001036065.1, UniProt: Q92918 |
Catalog # | MBS9209288 |
Price | $165, $370 |
Order / More Info | Phospho-MAP4K1 (Y381) Antibody from MYBIOSOURCE INC. |
Product Specific References | Hu M.C.-T., Genes Dev. 10:2251-2264(1996). Beausoleil S.A., Proc. Natl. Acad. Sci. U.S.A. 101:12130-12135(2004). Wissing J., Mol. Cell. Proteomics 6:537-547(2007). |