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Antigenic Specificity | ACIN1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | 1.1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total ACIN1 protein. Apoptosis is defined by several morphologic nuclear changes, including chromatin condensation and nuclear fragmentation. This gene encodes a nuclear protein that induces apoptotic chromatin condensation after activation by caspase-3, without inducing DNA fragmentation. This protein has also been shown to be a component of a splicing-dependent multiprotein exon junction complex (EJC) that is deposited at splice junctions on mRNAs, as a consequence of pre-mRNA splicing. It may thus be involved in mRNA metabolism associated with splicing. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthetic peptide corresponding to a region derived from internal residues of human apoptotic chromatin condensation inducer 1 |
Other Names | [ACN; ACINUS; fSAP152] |
Gene, Accession # | [ACIN1], Gene ID: 22985, NCBI: NP_001158286.1, UniProt: Q9UKV3 |
Catalog # | MBS9413998 |
Price | $255 |
Order / More Info | ACIN1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |