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Antigenic Specificity | PRKAG1/2/3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: PRKAG1/2/3 antibody detects endogenous levels of total PRKAG1/2/3. Function: AMP/ATP-binding subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Gamma |
Immunogen | Immunogen: A synthesized peptide Predicted Cross Reactivity: Pig, Zebrafish, Bovine, Sheep, Rabbit, Dog, Chicken, Xenopus Similarity: Pig (100%), Zebrafish (91%), Bovine (100%), Sheep (100%), Rabbit (100%), Dog (100%), Chicken (100%), Xenopus (90%) |
Other Names | [5' AMP activated protein kinase gamma 1 subunit; 5' AMP activated protein kinase subunit gamma 1; 5''-AMP-activated protein kinase subunit gamma-1; AAKG1_HUMAN; AMP activated protein kinase noncatalytic gamma 1 subunit; AMPK gamma 1 chain; AMPK gamma1; AMPK subunit gamma-1; AMPKg; MGC8666; PRKAG 1; PRKAG1; Protein kinase AMP activated gamma 1 non catalytic subunit; protein kinase, AMP-activated, noncatalytic gamma-1; 5''-AMP-activated protein kinase subunit gamma-2; AAKG; AAKG2; AAKG2_HUMAN; AMPK gamma2; AMPK subunit gamma 2; AMPK subunit gamma-2; CMH6; H91620p; Prkag2; Protein kinase AMP activated gamma 2 non catalytic subunit; WPWS; 5 AMP activated protein kinase subunit gamma 3; 5''-AMP-activated protein kinase subunit gamma-3; AAKG3_HUMAN; AMPK gamma 3 chain; AMPK gamma3; AMPK subunit gamma-3; AMPKG3; PRKAG3; Protein kinase AMP activated gamma 3 non catalytic subunit] |
Gene, Accession # | [PRKAG1], Gene ID: 5571, NCBI: NP_001193638.1, UniProt: P54619 |
Catalog # | MBS9604676 |
Price | $240, $280 |
Order / More Info | PRKAG1/2/3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |