Mac-1 (CD11b) (Mouse) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMac-1 (CD11b) (Mouse)
Clonemonoclonal
Host SpeciesMouse
Reactive Speciesrat
IsotypeIgG1
Formatunconjugated
Size0.1 mg
Concentration1ug/ul
ApplicationsFlow Cytometry (FC/FACS)
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DescriptionThis antibody recognizes rat Mac-1 (CD11b). The hybridoma was formed by the fusion of mouse myeloma line NS-1 with splenocytes from mice immunized with rat neutrophils. The antibody is routinely tested by flow cytometry. CD11b is an alpha subunit of Mac-1, also known as CR3. CD11b is the receptor for the C3bi fragment of complement. This receptor is involved in bacterial phagocytosis. A reduction in neutrophil CD11b expression after severe traumatic injury correlates with increased septic complications. CD11b is a component of integrins, important for adhesion of neutrophils to surfaces. Mac-1 exists as a chemoattractant activation-dependent molecule that undergoes a conformational change upon stimulation. Expression of new epitopes on Mac-
ImmunogenImmunogen: Rat neutrophils
Other Names[Mac 1]
Gene, Accession #[Mac-1]
Catalog #MBS4158175
Price$630
Order / More InfoMac-1 (CD11b) (Mouse) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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