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Antigenic Specificity | Mac-1 (CD11b) (Mouse) |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | rat |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.1 mg |
Concentration | 1ug/ul |
Applications | Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody recognizes rat Mac-1 (CD11b). The hybridoma was formed by the fusion of mouse myeloma line NS-1 with splenocytes from mice immunized with rat neutrophils. The antibody is routinely tested by flow cytometry. CD11b is an alpha subunit of Mac-1, also known as CR3. CD11b is the receptor for the C3bi fragment of complement. This receptor is involved in bacterial phagocytosis. A reduction in neutrophil CD11b expression after severe traumatic injury correlates with increased septic complications. CD11b is a component of integrins, important for adhesion of neutrophils to surfaces. Mac-1 exists as a chemoattractant activation-dependent molecule that undergoes a conformational change upon stimulation. Expression of new epitopes on Mac- |
Immunogen | Immunogen: Rat neutrophils |
Other Names | [Mac 1] |
Gene, Accession # | [Mac-1] |
Catalog # | MBS4158175 |
Price | $630 |
Order / More Info | Mac-1 (CD11b) (Mouse) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |