GAD1/GAD67 (GABAergic Neuronal Marker) Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-GAD1/GAD67 (GABAergic Neuronal Marker) antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | GAD1/GAD67 (GABAergic Neuronal Marker) |
| Clone | [GAD1/2391] |
| Host Species | Mouse |
| Reactive Species | human. |
| Isotype | IgG1, kappa |
| Format | unconjugated |
| Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
| Concentration | n/a |
| Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) Formalin |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This MAb recognizes a protein of 67kDa, which is identified as glutamic acid decarboxylase 1 (GDA1). There are two forms of glutamic acid decarboxylases (GADs) that are found in the brain: GAD65 (also known as GAD2) and GAD67 (also known as GAD1. GAD65 and GAD67 are members of the group II decarboxylase family of proteins and are responsible for catalyzing the rate-limiting step in the production of GABA (gamma-aminobutyric acid) from L-glutamic acid. Although both GADs are found in the brain, GAD65 localizes to synaptic vesicle membranes in nerve terminals, while GAD67 is distributed throughout the cell. GAD67 is responsible for the basal levels of GABA synthesis. In the case of a heightened demand for GABA in neurotransmission, GAD65 will |
| Immunogen | Immunogen: Recombinant human GAD1 (GAD67) protein fragment (around aa 72-135) Cellular Localization: Cytoplasmic |
| Other Names | [67kDa glutamic acid decarboxylase; CPSQ1; DCE1; GAD67; GAD1; Glutamate decarboxylase 1; SCP] |
| Gene, Accession # | [GAD1], Gene ID: 2571, NCBI: NP_000808.2, UniProt: Q99259 |
| Catalog # | MBS4380441 |
| Price | $190, $340, $340 |
| Order / More Info | GAD1/GAD67 (GABAergic Neuronal Marker) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Kaufman DL, Erlander MG, Clare-Salzler M, Atkinson MA, Maclaren NK, Tobin AJ. Autoimmunity to two forms of glutamate decarboxylase in insulin-dependent diabetes mellitus. J Clin Invest. 1992 Jan; 89(1):283-92. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies