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Antigenic Specificity | Podoplanin/D2-40 |
Clone | [D2-40] |
Host Species | Mouse |
Reactive Species | human, rat, mouse |
Isotype | IgG1 |
Format | unconjugated |
Size | 5 Control Slides, 0.1 mL (Concentrate), 3 ml (Prediluted) |
Concentration | n/a |
Applications | Immunohistochemistry-Paraffin/Frozen (IHC-P/F) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Summary and Explanation: Podoplanin is a transmembrane mucoprotein (38 kDa) recognized by the D2-40 monoclonal antibody. Podoplanin is specifically expressed in the endothelium of lymphatic capillaries but not in the blood vasculature. In normal skin and kidney, podoplanin is co-localized with VEGFR3/FLT4, another marker for lymphatic endothelial cells. Podoplanin is selectively expressed in lymphatic endothelium as well as Lymphangiomas, Kaposi's Sarcomas and in subset Angiosarcomas with probable lymphatic differentiation. Podoplanin has also been shown to be expressed in Epithelioid Mesotheliomas, Hemangioblastomas and Seminomas. |
Immunogen | Immunogen: Resected tissue from dysgeminoma of the ovary. Localization: Cytoplasmic. Control: Tonsil, Lymph Node, Lymphangioma |
Other Names | n/a |
Gene, Accession # | n/a |
Catalog # | MBS370061 |
Price | $130, $210, $255 |
Order / More Info | Podoplanin/D2-40 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |