BIM/BOD (IN2) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | BIM/BOD (IN2) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | phycoerythrin (RPE) conjugate |
| Size | 0.1 mg |
| Concentration | 1mg/mL |
| Applications | Western Blot (WB), Immunocytochemistry (ICC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Background Info: Detects a 23kDa protein corresponding to the molecular mass of Bim on SDS PAGE immunoblots. Scientific Background: Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bim/BOD is a group of three splice variants, BimEL, BimL and BimS, with apparent molecular masses of ~23, 16, and 13 kDa, respectively. Bcl-2 homology 3 (BH3) domain is a potent death domain. BH3 domain containing pro-apoptotic proteins, including Bad, Bax, Bid, Bik, and Hrk, form a growing subclass of the Bcl-2 family. A novel BH3 domain containing protein was recently identified and designated Bim or BOD in human, mouse and rat (1,2). Bim/BOD interacts with diverse members in the pro-survival Bcl-2 s |
| Immunogen | n/a |
| Other Names | [BCL2 like protein 11; Bcl2 interacting mediator of cell death; Bcl2 interacting protein Bim; BCL@ like 11; BAM; BimEl; BimL; BOD; BIM beta 6; BIM Beta7; BIM alpha 3; BIM alpha4; BIM alpha5; BIM alpha6], [BCL2L11; BCL2L11; BAM; BIM; BOD; BIM; Bcl2-L-11] |
| Gene, Accession # | Gene ID: 10018, NCBI: NP_619527.1, UniProt: O43521 |
| Catalog # | MBS804938 |
| Price | $435 |
| Order / More Info | BIM/BOD (IN2) Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. O'Connor L, Strasser A, O'Reilly LA, et al. Bim: a novel member of the Bcl-2 family that promotes apoptosis. EMBO J. 1998; 17:384-395. 2. Hsu SY, Lin P, and Hsueh AJ BOD (Bcl-2-related ovarian death gene) is an ovarian BH3 domain-containing proapoptotic Bcl-2 protein capable of dimerization with diverse antiapoptotic Bcl-2 members. Mol. Endocrinol. 1998; 12:1432-40. |
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MYBIOSOURCE INC.
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