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Antigenic Specificity | SNW1 - C-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene, a member of the SNW gene family, encodes a coactivator that enhances transcription from some Pol II promoters. This coactivator can bind to the ligand-binding domain of the vitamin D receptor and to retinoid receptors to enhance vitamin D-, retinoic acid-, estrogen-, and glucocorticoid-mediated gene expression. It can also function as a splicing factor by interacting with poly(A)-binding protein 2 to directly control the expression of muscle-specific genes at the transcriptional level. Finally, the protein may be involved in oncogenesis since it interacts with a region of SKI oncoproteins that is required for transforming activity. Alternative splicing results in multiple transcript variants. |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human SNW1 |
Other Names | [SNW domain-containing protein 1 isoform 2; SNW domain-containing protein 1; SNW domain-containing protein 1; SNW domain containing 1; Nuclear protein SkiP; Nuclear receptor coactivator NCoA-62; Ski-interacting protein] |
Gene, Accession # | [SNW1], Gene ID: 22938, NCBI: NP_036377.1, UniProt: Q13573 |
Catalog # | MBS3220013 |
Price | $335 |
Order / More Info | SNW1 - C-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |