Edit |   |
---|---|
Antigenic Specificity | Mouse CXCR4 |
Clone | polyclonal |
Host Species | Goat |
Reactive Species | human, mouse. reactivity: rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 0.05 mg |
Concentration | 1 mg/ml |
Applications | Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody binds to CXCR4 receptor on mouse spleen leukocytes as determined by immunocytochemistry. CXCR4, a Chemokine Receptor involved in organ vascularization, neuronal cell migration, and patterning of the central nervous system during development. It binds stromal cell-derived factor 1 (SDF1, also called PBFS) and mediates migration of resting leukocytes and is unique in homing hematopoietic progenitors to bone marrow. These properties suggest that CXCR4 is involved in tumor cell migration and local tumor invasion. |
Immunogen | Immunogen: CXCR4 antibody was raised against ySEEVGSGDYDSNKEPCFRDENVHFNR corresponding to the N-terminal extracellular domain of mouse CXCR4 receptor. Percent identity by BLAST analysis: Mouse (100%); Rat (93%); Baboon, Monkey, Marmoset, Elephant, Rabbit (81%). Epitope: aa14-40. Usage summary: Immunohistochemistry: MBS242498 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate |
Other Names | [CXCR4 (aa14-40) IHC-plus; CXCR4; CD184; CD184 antigen; Cmkar4; Cxc chemokine receptor 4; CXCR-4; CXC-R4; D2S201E; FB22; Fusin; HM89; LCR1; NPY3R; NPYRL; NPYY3R; Npyy3; HSY3RR; SDF-1 receptor; WHIM; C-x-c chemokine receptor 4; LESTR; Neuropeptide Y receptor Y3; NPYR; Mouse CXCR4], [CXCR4; CXCR4; FB22; HM89; LAP3; LCR1; NPYR; WHIM; CD184; LAP-3; LESTR; NPY3R; NPYRL; HSY3RR; NPYY3R; D2S201E; CXC-R4; CXCR-4; LESTR; LAP-3; LPS-associated protein 3; SDF-1 receptor] |
Gene, Accession # | [CXCR4], Gene ID: 7852, NCBI: NP_003458.1, UniProt: P61073 |
Catalog # | MBS242498 |
Price | $530 |
Order / More Info | Mouse CXCR4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |