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Antigenic Specificity | CARD9 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Adapter protein that plays a key role in innate immune response to a number of intracellular pathogens, such as C.albicans and L.monocytogenes. Is at the crossroads of ITAM-tyrosine kinase and the Toll-like receptors (TLR) and NOD2 signaling pathways. Probably controls various innate immune response pathways depending on the intracellular pathogen. In response to L.monocytogenes infection, acts by connecting NOD2 recognition of peptidoglycan to downstream activation of MAP kinases (MAPK) without activating NF-kappa-B. Also involved in activation of myeloid cells via classical ITAM-associated receptors and TLR: required for TLR-mediated activation of MAPK, while it is not required for TLR-induced activation of NF-kappa-B (By similarity). Con |
Immunogen | Immunogen: Recombinant human Caspase recruitment domain-containing protein 9 protein (237-536aa) Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-49408 / sc-49405 / sc-99054 |
Other Names | [hCARD9; CARD9], [CARD9; CARD9; CANDF2; hCARD9; hCARD9] |
Gene, Accession # | [CARD9], Gene ID: 64170, NCBI: NP_434700.2, UniProt: Q9H257 |
Catalog # | MBS1494821 |
Price | $120, $160 |
Order / More Info | CARD9 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |