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Antigenic Specificity | Heregulin-1/Neuregulin-1 (Breast and Urothelial Marker) |
Clone | [NRG1/2710] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, kappa |
Format | purified |
Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
Concentration | n/a |
Applications | Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Heregulin-1 is a membrane glycoprotein that mediates cell-cell signaling and plays a critical role in the growth and development of multiple organ systems. An extraordinary variety of different isoforms are produced from this gene through alternative promoter usage and splicing. These isoforms are expressed in a tissue-specific manner and differ significantly in their structure, and are classified as types I, II, III, IV, V and VI. Dysregulation of this gene has been linked to diseases such as cancer, schizophrenia, and bipolar disorder (BPD). |
Immunogen | Immunogen: Recombinant fragment of human Neuregulin-1 (NRG1) protein (around aa 21-242) (exact sequence is proprietary) |
Other Names | [Acetylcholine receptor-inducing activity (ARIA); Breast cancer cell differentiation factor p45; Glial growth factor (GGF2); Heregulin-1; Heregulin; alpha (45kD; ERBB2 p185-activator); HGL; HRG1; HRGA; MST131; Neu Differentiation Factor (NDF); Neuregulin-1; NRG1; Sensory and Motor Neuron-Derived Factor (SMDF)] |
Gene, Accession # | [NRG1], Gene ID: 3084, NCBI: NP_001153467.1, UniProt: Q02297 |
Catalog # | MBS4380978 |
Price | $190, $340, $340 |
Order / More Info | Heregulin-1/Neuregulin-1 (Breast and Urothelial Marker) Antibody from MYBIOSOURCE INC. |
Product Specific References | Meyer, D., et al. 1997. Isoform-specific expression and function of neuregulin. Development 124: 3575-3586. |