PDGF-A Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPDGF-A
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
FormatProtein G purified
Size0.1 mg, 0.2 mg
Concentrationn/a
ApplicationsWestern Blot (WB), IHC (Immunohistochemistry), ELISA (EIA)
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DescriptionPDGF is synthesized mainly by megakaryocytes. It is stored in the alpha granules of platelets from which it is released after cell activation of platelets. Platelets synthesize a mixture of the three possible isoforms (BB,AB,AA) while fibroblasts stimulated with EGF synthesize AA homodimers. PDGF receptors are expressed in fibroblasts, osteoblasts, chondroblasts, smooth muscle cells, glial cells, and endothelial cells.Two related receptors, are PDGFRalpha (CD140a) or PDGFRbeta (CD140b).In contrast to many other cytokines PDGF is not released into the circulation. PDGF binds to several plasma proteins and also to proteins of the extracellular matrix which facilitates local concentration of the factor. The factor functions as a local autocrin
ImmunogenSource Note: Polyclonal PDGF-A antibody was produced from sera of rabbits immunized with synthetic protein containing PDGF-A antigenic determinants.
Other Names[Rabbit PDGF-A purified; pdgf-aa; platelet derived growth factor;; pab], [PDGFA; PDGF1; PDGF subunit A]
Gene, Accession #[PDGF], Gene ID: 5154, NCBI: NP_002598.4, UniProt: P04085
Catalog #MBS551005
Price$280, $385
Order / More InfoPDGF-A Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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