Edit |   |
---|---|
Antigenic Specificity | TIA1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | 1.4mg/ml |
Applications | Immunohistochemistry (IHC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total TIA1 protein. The product encoded by this gene is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15-kDa protein that is thought to be derived from the carboxyl terminus of the 40-kDa product by proteolytic processing. Alternative splicing resulting in different isoforms of this gene product has been described in the literature. |
Immunogen | Immunogen: Full length fusion protein Immunogen Type: Protein |
Other Names | [WDM; TIA-1] |
Gene, Accession # | [TIA1], Gene ID: 7072, NCBI: NP_071320.2, UniProt: P31483 |
Catalog # | MBS9416960 |
Price | $255 |
Order / More Info | TIA1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |