MIA3 - C-terminal region Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMIA3 - C-terminal region
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionPlays a role in the transport of cargos that are too large to fit into COPII-coated vesicles and require specific mechanisms to be incorporated into membrane-bound carriers and exported from the endoplasmic reticulum. This protein is required for collagen VII (COL7A1) secretion by loading COL7A1 into transport carriers. It may participate in cargo loading of COL7A1 at endoplasmic reticulum exit sites by binding to COPII coat subunits Sec23/24 and guiding SH3-bound COL7A1 into a growing carrier. Does not play a role in global protein secretion and is apparently specific to COL7A1 cargo loading. However, it may participate in secretion of other proteins in cells that do not secrete COL7A1. It is also specifically required for the secretion of
ImmunogenImmunogen: The immunogen is a synthetic peptide directed towards the C terminal region of Human MIA3
Other Names[transport and Golgi organization protein 1 homolog isoform 2; Melanoma inhibitory activity protein 3; transport and Golgi organization protein 1 homolog; MIA SH3 domain ER export factor 3; C219-reactive peptide; D320; Transport and Golgi organization protein 1]
Gene, Accession #[MIA3], Gene ID: 375056, NCBI: NP_001287796.1, UniProt: Q5JRA6
Catalog #MBS3222711
Price$335
Order / More InfoMIA3 - C-terminal region Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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