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Antigenic Specificity | Mouse MAP3K7 / TAK1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | bovine, dog, Xenopus, guinea pig, hamster, human, monkey, mouse, porcine, rabbit, rat, sheep |
Isotype | n/a |
Format | Protein A purified |
Size | 0.05 mg |
Concentration | 1 mg/ml |
Applications | Immunohistochemistry (IHC - Paraffin), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Detects an ~70 kD protein, corresponding to the apparent molecular mass of TAK1 on SDS-PAGE immunoblots. MEKK7, known as TAK1 for transforming growth factor (TGF) beta-activated kinase-1, is a MLK (MAP3K) type protein kinase which is associated with several signaling pathways. The protein contains a N-terminal protein kinase domain preceeded by a short regulatory motif and followed by a C-terminal extension of unknown function. TAK1 is activated by TGF beta and tumor necrosis factor (TNF). |
Immunogen | Immunogen Description: Synthetic peptide based on mouse TAK1 (residues 563-579) (1) with a cysteine C residue added and the peptide coupled to KLH. |
Other Names | [MAP3K7 / TAK1 (aa563-579) IHC-plus; MAP3K7; MEKK7; TGF-beta activated kinase 1; TGF1a; TAK1; TGF-beta-activated kinase 1; Mouse MAP3K7; TAK1], [TAK1] |
Gene, Accession # | [MAP3K7], Gene ID: 6885, NCBI: NP_003179.1, UniProt: O43318 |
Catalog # | MBS244767 |
Price | $530 |
Order / More Info | Mouse MAP3K7 / TAK1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |