Caspase 10 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCaspase 10
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatimmunogen affinity purified
Size0.05 mL, 0.1 mL
Concentration1.0 mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
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DescriptionThe antibody detects endogenous levels of total Caspase 10 protein. Involved in the activation cascade of caspases responsible for apoptosis execution. Recruited to both Fas- and TNFR-1 receptors in a FADD dependent manner. May participate in the granzyme B apoptotic pathways. Cleaves and activates caspase-3, -4, -6, -7, -8, and -9. Hydrolyzes the small- molecule substrates, Tyr-Val-Ala-Asp-|-AMC and Asp-Glu-Val-Asp-|-AMC. Isoform C is proteolytically inactive.Frank C. Kischkel, J. Biol. Chem., Nov 2001; 276: 46639 - 46646.Ingo H. Engels, Mol. Cell. Biol., Apr 2005; 25: 2808 - 2818.Daniela Sciaky, J. Immunol., Apr 2000; 164: 3806.Jin Wang, PNAS, Nov 2001; 98: 13884.
ImmunogenImmunogen Type: Peptide Immunogen Description: Synthesized peptide derived from human Caspase 10.
Other Names[ALPS2; CASP10B; FLICE2; Caspase 10 isoform a preproprotein; Caspase 10 isoform b preproprotein]
Gene, Accession #Gene ID: 843, NCBI: NP_001193453.1, UniProt: Q92851
Catalog #MBS9401526
Price$200, $255
Order / More InfoCaspase 10 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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