Caspase 4 Picoband Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Caspase 4 Picoband |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | unconjugated |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | ELISA (EIA), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Description: Caspase 4 is an enzyme that proteolytically cleaves other proteins at an aspartic acid residue, and belongs to a family of cysteine proteases called caspases. The Caspase 4 gene is mapped to a P1 clone containing the ICE gene, which is located at chromosome 11q22.2-q22.3. It contains 8 coding exons. The function of caspase 4 is not fully known, but it is believed to be an inflammatory caspase, along with caspase 1, caspase 5 (and the murine homolog caspase 11), with a role in the immune system.Protein Function: Proinflammatory caspase (PubMed: 8702803, PubMed: 9038361, PubMed: 25119034). Essential effector of NLRP3 inflammasome- dependent CASP1 activation and IL1B and IL18 secretion in response to non-canonical activators, |
| Immunogen | Immunogen: E Coli-derived mouse Caspase 4 recombinant protein (Position: E108-T195). Subcellular Localization: Cytoplasm, cytosol. Tissue Specificity: Widely expressed, including in thymus, lung and spleen (at protein level). Very low levels, if any, in the brain. |
| Other Names | [Caspase-4; CASP-4] |
| Gene, Accession # | [Casp4], Gene ID: 12363, NCBI: NP_031635.2, UniProt: P70343 |
| Catalog # | MBS1750803 |
| Price | $280 |
| Order / More Info | Caspase 4 Picoband Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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