Edit |   |
---|---|
Antigenic Specificity | ADAMTS4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for A disintegrin and metalloproteinase with thrombospondin motifs 4(ADAMTS4) detection. Tested with WB in Human, Mouse, Rat. Background: ADAMTS4, A disintegrin and metalloproteinase with thrombospondin motifs 4 is an enzyme that in humans is encoded by the ADAMTS4 gene. ADAMTS4 is a member of the large ADAMTS family of zinc-dependent proteases. The human ADAMTS4 gene is mapped to chromosome 1 by somatic cell hybrid analysis. The enzyme encoded by this gene lacks a C-terminal TS motif. It is responsible for the degradation of aggrecan, a major proteoglycan of cartilage, and brevican, a brain-specific extracellular matrix protein. The cleavage of aggrecan and brevican suggests key roles of this enz |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human ADAMTS4 (820-837aa RRAQILEILRRRPWAGRK), different from the related rat and mouse sequences by three amino acids. |
Other Names | [A disintegrin and metalloproteinase with thrombospondin motifs 4(ADAM-TS 4/ADAM-TS4/ADAMTS-4); ADAM metallopeptidase with thrombospondin type 1 motif, 4; A disintegrin and metalloproteinase with thrombospondin motifs 4; A disintegrin like and metalloprotease(reprolysin type) with thrombospondin type 1 motif 4; A disintegrin like and metalloprotease with thrombospondin type 1 motif 4; ADAM metallopeptidase with thrombospondin type 1 motif 4; ADAM TS 4; ADAM TS4; ADAM-TS 4; ADAM-TS4; ADAMTS 2; ADAMTS 4; ADAMTS-4; ADAMTS2; ADAMTS4; ADAMTS4 protein; ADMP 1; ADMP-1; ADMP1; Aggrecanase 1; Aggrecanase-1; Aggrecanase1; ATS4_HUMAN; KIAA0688], [ADAMTS4; ADAMTS4; ADMP-1; ADAMTS-2; ADAMTS-4; KIAA0688; ADAM-TS 4; ADAM-TS4; ADAMTS-4] |
Gene, Accession # | [ADAMTS4], Gene ID: 9507, NCBI: O75173.3, UniProt: O75173 |
Catalog # | MBS175649 |
Price | $280 |
Order / More Info | ADAMTS4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |