RGS14 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityRGS14
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA)
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DescriptionSpecificity: RGS14 antibody detects endogenous levels of total RGS14. Function: Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. Besides, modulates signal transduction via G protein alpha subunits by functioning as a GDP-dissociation inhibitor (GDI). Has GDI activity on G(i) alpha subunits GNAI1 and GNAI3, but not on GNAI2 and G(o) alpha subunit GNAO1. Has GAP activity on GNAI0, GNAI2 and GNAI3. May act as a scaffold integrating G protein and Ras/Raf MAPkinase signaling pathways. Inhibits platelet-derived growth factor (PDGF)-stimulated ERK1/ERK2 phosphorylation; a process depending on
ImmunogenImmunogen: A synthesized peptide Subcellular Location: Nucleus. Nucleus > PML Body. Cytoplasm. Membrane. Cell Membrane. Cytoplasm > Cytoskeleton > Centrosome. Cytoplasm > Cytoskeleton > Spindle. Cytoplasm > Cytoskeleton > Spindle Pole. Cell Projection > Dendrite. Cell Projection > Dendritic Spine. Cell Junction > Synapse > Postsynaptic Cell Membrane > Postsynaptic Density. Associates with the perinuclear sheaths of microtubules (MTs) surrounding the pronuclei, prior to segregating to the anastra
Other Names[Highly similar to rap1/rap2 interacting protein; OTTHUMP00000223586; OTTHUMP00000223587; Regulation of G protein signaling 14; Regulator of G protein signaling 14; Regulator of G protein signalling 14; Regulator of G-protein signaling 14; RGS 14; RGS14; RGS14_HUMAN]
Gene, Accession #[RGS14], Gene ID: 10636, NCBI: NP_006471.2, UniProt: O43566
Catalog #MBS9605870
Price$240, $280
Order / More InfoRGS14 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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