WWOX Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-WWOX antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | WWOX |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: WWOX antibody detects endogenous levels of total WWOX. Function: Putative oxidoreductase. Acts as a tumor suppressor and plays a role in apoptosis. Required for normal bone development (By similarity). May function synergistically with p53/TP53 to control genotoxic stress-induced cell death. Plays a role in TGFB1 signaling and TGFB1-mediated cell death. May also play a role in tumor necrosis factor (TNF)-mediated cell death. Inhibits Wnt signaling, probably by sequestering DVL2 in the cytoplasm.Subunit Structure: Interacts with TP53, p73/TP73 and MAPK8. Interacts with MAPT/TAU, RUNX2 and HYAL2 (By similarity). Forms a ternary complex with TP53 and MDM2. Interacts with ERBB4, LITAF and WBP1. Interacts with DVL1, DVL2 and DVL |
| Immunogen | Immunogen: A synthesized peptide Subcellular Location: Cytoplasm. Nucleus. Mitochondrion. Golgi Apparatus. Partially localizes to the mitochondria. Translocates to the nucleus upon genotoxic stress or TNF stimulation (By similarity). Translocates to the nucleus in response to TGFB1. Isoform 5 and isoform 6 may localize in the nucleus. Tissue Specificity: Widely expressed. Strongly expressed in testis, prostate, and ovary. Overexpressed in cancer cell lines. Isoform 5 and isoform 6 may only be ex |
| Other Names | [5330426P09Rik; 9030416C10Rik; Aberrant WW domain-containing oxidoreductase; D16S432E; EC 1.1.1.-; EIEE28; FOR; FRA16D; Fragile site FRA16D oxidoreductase; Fragile site FRA16D Oxireductase; HHCMA56; MGC55975; PRO0128; Putative oxidoreductase; SCAR12; SDR41C1; Short chain dehydrogenase/reductase family 41C, member 1; WOX1; WW domain containing oxidoreductase; WW domain-containing oxidoreductase; WW domain-containing protein WWOX; wwox; WWOX_HUMAN; zgc:55975] |
| Gene, Accession # | [WWOX], Gene ID: 51741, NCBI: NP_001278926.1, UniProt: Q9NZC7 |
| Catalog # | MBS9605090 |
| Price | $240, $280 |
| Order / More Info | WWOX Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies