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Antigenic Specificity | Human IL-21 |
Clone | [3A3-N2] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, kappa |
Format | phycoerythrin (PE) conjugate |
Size | 20 tests, 50 tests, 100 tests |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Interleukin 21 (IL-21) is a potent immunomodulatory cytokine mainly produced by NKT and CD4+ T-cells, particularly the inflammatory Th17 subset, and has pleiotropic effects on both innate and adaptive immune responses. These actions include positive effects such as enhancing proliferation of NK cells and cytotoxic T cells, and inhibitory effects on the antigen-presenting function of dendritic cells. It can also be proapoptotic for B cells and NK cells. Studies have shown that IL-21 is also an autocrine cytokine that potently induces Th17 differentiation, suppresses Foxp3 expression, and serves as a target for treating inflammatory diseases. |
Immunogen | n/a |
Other Names | [Interleukin-21; IL-21; Za11] |
Gene, Accession # | [IL-21], Gene ID: 59067, NCBI: NP_001193935.1, UniProt: Q9HBE4 |
Catalog # | MBS2559474 |
Price | $100, $125, $165 |
Order / More Info | Human IL-21 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |