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Antigenic Specificity | Osteoprotegerin/TNFRSF11B |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, Flow Cytometry (FC/FACS), Direct ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: No cross reactivity with other proteins. Description: Rabbit IgG polyclonal antibody for Osteoprotegerin/TNFRSF11B detection. Tested with WB, IHC-P, FCM, Direct ELISA in Human; Mouse; Rat.Background: Tumor necrosis factor receptor superfamily member 11B (TNFRSF11B), also known as OPG, is a protein that in humans is encoded by the TNFRSF11B gene. OPG is a cytokine receptor, and a member of the tumor necrosis factor (TNF) receptor superfamily. By analysis of radiation hybrids, TNFRSF11B gene was mapped to chromosome 8q24. OPG is a decoy receptor for the receptor activator of nuclear factor kappa B ligand (RANKL). By binding RANKL, OPG inhibits nuclear kappa B (NF-kappaB) which is a central and rapid acting transcription f |
Immunogen | Immunogen: E. coli-derived human Osteoprotegerin/TNFRSF11B recombinant protein (Position: Q247-R296). |
Other Names | [Tumor necrosis factor receptor superfamily member 11B; Osteoclastogenesis inhibitory factor; Osteoprotegerin; TNFRSF11B; OCIF; OPG] |
Gene, Accession # | [TNFRSF11B], Gene ID: 4982, NCBI: NP_002537.3, UniProt: O00300 |
Catalog # | MBS1752842 |
Price | $315 |
Order / More Info | Osteoprotegerin/TNFRSF11B Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Krakauer T (2008). Nuclear factor-kappa B: fine-tuning a central integrator of diverse biologic stimuli. Int. Rev. Immunol. 27 (5): 286-92. 2. Khosla S (December 2001). Minireview: the OPG/RANKL/RANK system. Endocrinology 142 (12): 5050-5. 3. Schoppet M, Preissner KT, Hofbauer LC (April 2002). RANK ligand and osteoprotegerin: paracrine regulators of bone metabolism and vascular function. Arterioscler. Thromb. Vasc. Biol. 22 (4): 549-53. |