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Antigenic Specificity | Human KCNJ11 / Kir6.2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 0.05 mL |
Concentration | 1 mg/ml |
Applications | Immunohistochemistry (IHC - Paraffin), Immunofluorescence (IF), Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Kir6.2 Antibody detects endogenous levels of total Kir6.2 protein. Kir6.2/Kcnj11, an ATP sensitive inwardly-rectifying potassium channel, was originally isolated from an insulinoma library. Actual conductance requires association with the sulfonylurea receptor. This receptor is inhibited by sulfonylureas and activated by diazoxide. Mutations in the KNCJ11 gene are found in patients with permanent diabetes mellitus of infancy and hyperinsulinemic hypoglycemia. |
Immunogen | Immunogen Description: Synthetic peptide from human Kir6.2 (aa190-239). |
Other Names | [KCNJ11 / Kir6.2 (aa190-239) IHC-plus; KCNJ11; BIR; IKATP; HHF2; PHHI; TNDM3; Beta-cell KATP channel; KIR6.2; Human KCNJ11; Kir6.2], [Kir6.2] |
Gene, Accession # | [KCNJ11], Gene ID: 3767, NCBI: NP_000516.3, UniProt: Q14654 |
Catalog # | MBS243980 |
Price | $530 |
Order / More Info | Human KCNJ11 / Kir6.2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |