C-Raf (C-terminus) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | C-Raf (C-terminus) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, rat, mouse |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | ELISA, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This antibody was affinity purified using C-Raf (Cterminus) peptide. The purified antibody detects C-Raf in western blots of a purified GST-fusion protein containing human C-Raf. The Ras-Raf-MAP kinase signaling pathway is involved in control of cell proliferation and differentiation. The Raf kinase family includes A-Raf, BRaf, and C-Raf. Each family member has three highly conserved regions (CR1-3). The N-terminal CR1 contains the Ras-GTP-binding domain. The CR2 contains a negative regulatory serine residue (C-Raf (S259)/B-Raf (S365)) that may bind 14-3-3 proteins. The CR3 is the catalytic domainthat contains phosphorylation sites for Raf-regulating enzymes within two segments, the N-region and the activation segment. Activation of C-Raf |
| Immunogen | Immunogen: C-Raf (C-terminus) synthetic peptide (coupled to KLH) corresponds to amino acids 637 to 648 in human C-Raf. This sequence is conserved in C-Rafs from many species, and is not found in A-Raf or B-Raf. |
| Other Names | [Raf-1], [raf1a; raf1a; craf; raf1; c-raf; c-raf] |
| Gene, Accession # | Gene ID: 30716, UniProt: Q90458 |
| Catalog # | MBS472017 |
| Price | $325 |
| Order / More Info | C-Raf (C-terminus) Antibody from MYBIOSOURCE INC. |
| Product Specific References | • Mason, C.S. et al. (1999) EMBOJ 18(8):2137.• Zhu, J. et al. (2005). Mol. Biol. Cell 16:4733. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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