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Antigenic Specificity | GFRA1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes a member of the glial cell line-derived neurotrophic factor receptor (GDNFR) family of proteins. The encoded preproprotein is proteolytically processed to generate the mature receptor. Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. This receptor is a glycosylphosphatidylinositol (GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for Hirschsprung disease. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is prot |
Immunogen | Immunogen: Recombinant protein of human GFRA1 |
Other Names | [GDNFR; GDNFRA; GFR-ALPHA-1; RET1L; RETL1; TRNR1] |
Gene, Accession # | [GFRA1], Gene ID: 2674, NCBI: NP_001138925.1, UniProt: P56159 |
Catalog # | MBS8545541 |
Price | $280 |
Order / More Info | GFRA1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |