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Antigenic Specificity | Caspase-6 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | dog, rat, mouse, human |
Isotype | n/a |
Format | serum |
Size | 0.05 mL |
Concentration | n/a |
Applications | Immunoprecipitation (IP), Immunohistochemistry (IHC) Formalin/Paraffin, Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Caspases belong to the cysteine-aspartic acid protease (Caspase) family which plays a major role in the transduction of the apoptotic signal and execution of apoptosis in mammalian cells. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This protein could be processed by caspases 7, 8 and 10, and is thought to function as a downstream. Caspase 3 (CPP32) and Caspase 6 (Mch2) are the major active caspases in apoptotic cells, and are activated in response to distinct apoptosis-inducing stimuli and in all cell lines analyzed. Both CPP32 and Mch2 are present in apoptotic cells as multiple active species. Caspa |
Immunogen | Immunogen Information: A recombinant catalytically active human Caspase-6 protein was used as the immunogen for this antibody |
Other Names | [Casp6; LOC103689977; rCG_28913; to Caspase-6; Caspase-6; Caspase-6], [LOC103689977; Casp6] |
Gene, Accession # | [Casp6], Gene ID: 103689977, NCBI: Q6AZ23, UniProt: Q6AZ23 |
Catalog # | MBS668574 |
Price | $270 |
Order / More Info | Caspase-6 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |