Wilms Tumor 1 (WT1) (Wilms Tumor & Mesothelial Marker) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Wilms Tumor 1 (WT1) (Wilms Tumor & Mesothelial Marker) |
| Clone | [WT1/1434R] |
| Host Species | Rabbit |
| Reactive Species | human. |
| Isotype | IgG |
| Format | unconjugated |
| Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
| Concentration | n/a |
| Applications | Immunohistology (Formalin-fixed) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Recognizes a 47-55kDa-tumor suppressor protein, identified as Wilm's Tumor (WT1) protein. The antibody reacts with all isoforms of the full-length WT1 and also identifies WT1 lacking exon 2-encoded amino acids, frequently found in subsets of sporadic Wilm's tumors. WT1, a sporadic and familial pediatric kidney tumor, is genetically heterogeneous. Wilm's tumor is associated with mutations of WT1, a zinc-finger transcription factor that is essential for the development of the metanephric kidney and the urogenital system. The WT1 gene is normally expressed in fetal kidney and mesothelium, and its expression has been suggested as a marker for Wilm's tumor and mesothelioma. WT1 protein has been identified in proliferative mesothelial cells, mali |
| Immunogen | Immunogen: Recombinant human full-length WT1 protein Cellular Localization: Nuclear and Cytoplasmic Positive Control: K562 cells. Wilm's Tumor, mesothelioma or fetal kidney. |
| Other Names | [WT1; AWT1; FWT1; GUD; NPHS4; WAGR; Wilms tumor 1] |
| Gene, Accession # | [WT1], Gene ID: 7490, NCBI: NP_000369.3, UniProt: P19544 |
| Catalog # | MBS4380288 |
| Price | $190, $340, $340 |
| Order / More Info | Wilms Tumor 1 (WT1) (Wilms Tumor & Mesothelial Marker) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Rauscher FJ. The WT1 Wilms tumor gene product: A developmentally regulated transcription factor in the kidney that functions as a tumor suppressor. FASEB J 1993; 7:896 |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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