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Antigenic Specificity | TIMELESS - C-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | cow, dog, guinea pig, horse, human, mouse, rat, sheep, yeast |
Isotype | n/a |
Format | Protein A purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against TIMELESS. It was validated on Western Blot using a cell lysate as a positive control.Target Description: The human Timeless protein interacts with both the circadian clock protein cryptochrome 2 and with the cell cycle checkpoint proteins Chk1 and the ATR-ATRIP complex and plays an important role in the DNA damage checkpoint response. Down-regulation of Timeless in human cells seriously compromises replication and intra-S checkpoints, indicating an intimate connection between the circadian cycle and the DNA damage checkpoints that is in part mediated by the Timeless protein. |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human TIMELESS |
Other Names | [protein timeless homolog isoform 1; Protein timeless homolog; protein timeless homolog; timeless circadian regulator] |
Gene, Accession # | [TIMELESS], Gene ID: 8914, NCBI: NP_003911, UniProt: Q9UNS1 |
Catalog # | MBS3204064 |
Price | $270 |
Order / More Info | TIMELESS - C-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |