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Antigenic Specificity | TNF receptor 1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat, bovine, dog, Drosophila, hamster, monkey, porcine, rabbit, sheep, Xenopus, yeast |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.05 mg, 0.2 mg |
Concentration | n/a |
Applications | Immmunohistochemistry (IHC) (PS), Immunoprecipitation (IP), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes human, mouse, rat, bovine, dog, Drosophila, hamster, monkey, pig, rabbit, sheep, Xenopus and yeast TNF-R1. Detects a band of 55kDa by Western blot. Tumor necrosis factor alpha (TNF- alpha ), also known as cachectin, is a 17.5 kDa 157 amino acid member of the TNF superfamily of cytokines that is a potent lymphoid factor with effects on a wide range of target cells. Active TNFalpha is produced in both soluble and membrane-anchored trimers by macrophages, NK cells, and T- and B-lymphocytes. TNF exerts proinflammatory signals via binding and inducing trimerization of TNF-receptor1 (TNF-R1) expressed on most normal and transformed cells, or to TNF-receptor 2 (TNF-R2), expressed on endothelial and most immune cells. TNF signaling regul |
Immunogen | Immunogen: Synthetic peptide corresponding to a portion of mouse TNF-R1. The sequence is completely conserved in rat and human. |
Other Names | [TNF], [Tnfrsf1a; Tnfrsf1a; FPF; p55; TNF-R; TNFAR; TNFRI; Tnfr1; p55-R; CD120a; TNF-R1; TNFR60; Tnfr-2; TNF-R-I; TNF-R55; TNFRp55; TNF-alphaR1; TNFalpha-R1; Tnfr-1; Tnfr1; TNF-R1; TNF-RI; TNFR-I] |
Gene, Accession # | [Tumor necrosis factor receptor 1; TNF-R1], Gene ID: 21937, NCBI: P25118.1, UniProt: P25118 |
Catalog # | MBS565174 |
Price | $295, $520 |
Order / More Info | TNF receptor 1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |