BIRC2 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-BIRC2 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | BIRC2 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | dog, Gerbil, mouse and rat. |
| Isotype | n/a |
| Format | serum |
| Size | 0.05 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC). Other applications not tested. |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Recognizes human BIRC2. cIAP1 (HIAP2, MIHB) is a member of the family of inhibitor of apoptosis proteins (IAP). IAPs suppress mitochondria-dependent and -independent apoptosis by binding to and inhibiting caspases through their BIR domains (reviewed in Liston et al, 2003; Wright and Duckett, 2005). Resistance towards apoptosis is a hallmark of cancer cells, and overexpression of IAPs can contribute to the development of cancer though inhibiting apoptosis. In addition to at least one BIR domain, some IAP members also have a RING-type finger motif at their carboxyl-terminal. The RING finger domain of several IAPs, including cIAP2, have E3 ubiquitin ligase activity and target the degradation of Smac/DIABLO through ubqiuitination. Smac/DIABLO i |
| Immunogen | Immunogen: Recombinant corresponding to full-length human BIRC2 |
| Other Names | BIRC2 (Baculoviral IAP Repeat-containing Protein 2, C-IAP1, IAP Homolog B, Inhibitor of Apoptosis Protein 2, IAP-2, hIAP-2, hIAP2, RING Finger Protein 48, TNFR2-TRAF-signaling Complex Protein 2, API1, IAP2, MIHB, RNF48) |
| Gene, Accession # | Gene ID: 329, NCBI: NP_001157, UniProt: Q13490 |
| Catalog # | MBS616492 |
| Price | $500 |
| Order / More Info | BIRC2 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies