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Antigenic Specificity | beta-Tubulin (10B1) |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human, mouse, rat, monkey |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: beta-Tubulin (10B1) Mouse mAb detects endogenous levels of total beta-tubulin protein. Tubulin is a major cytoskeleton component that has five distinct forms, designated alpha, beta, gamma, delta and epsilon Tubulin. alpha and beta Tubulins form heterodimers which multimerize to form a microtubule filament. There are five beta Tubulin isoforms (beta1, beta2, beta3, beta4A and beta4B) that are expressed in mammalian tissues. beta1 and beta4 are present throughout the cytosol, beta2 is present in the nuclei and nucleoplasm, and beta3 is a neuron-specific cytoskeletal protein. gamma Tubulin forms the gammasome, which is required for nucleating microtubule filaments at the centrosome. Both delta Tubulin and epsilon Tubulin are asso |
Immunogen | Source Note: This monoclonal antibody is produced by immunizing animals with a protein fragment within the carboxy terminus of human beta-tubulin. |
Other Names | n/a |
Gene, Accession # | NCBI: AAA32689.1 |
Catalog # | MBS435017 |
Price | $215, $275, $370 |
Order / More Info | beta-Tubulin (10B1) Antibody from MYBIOSOURCE INC. |
Product Specific References | 1.Weisenberg, R. 1981. Invited review: the role of nucleotide triphosphate in Actin and Tubulin assembly and function. Cell Motil. 1: 485-497. 2. Hoffman, P.N. 1988. Distinct roles of neurofilament and Tubulin gene expression in axonal growth. Ciba Found. Symp. 138: 192-204. 3. Zheng, Y., Jung, M.K. and Oakley, B.R. 1991. g Tubulin is present in Drosophila melanogaster and Homo sapiens and is associated with the centrosome. Cell 65: 817-823. |