Mouse CD81 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMouse CD81
Clone[Eat2]
Host SpeciesHamster
Reactive Speciesn/a
IsotypeIgG1
Formatfluorescein (FITC) conjugate
Size0.1 mg
ConcentrationIgG concentration 0.1 mg/ml
ApplicationsFlow cytometry (FC/FACS)
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DescriptionHamster anti Mouse CD81 antibody, clone Eat2 recognizes mouse and rat CD81, also known as TAPA-1 or Target of the antiproliferative antibody 1. CD81 is a 236 amino acid ~26 kDa multipass transmembrane protein belonging to the TM4SF family (UniProt: P35762). In rodents CD81 is expressed at much higher levels on resting B cells than on T cells, although increased expression on T cells is found following activation. Hamster anti Mouse CD81 antibody, clone Eat2 induces homotypic aggregation of B cells and inhibits anti Ig and IL-4 induced proliferation (Maecker et al. 2000). Eat 2 requires the presence of both extracellular loops of TAPA-1 for binding. Mice lacking CD81 demonstrate reduced fertility through impaired oocyte-sperm fusion, double
ImmunogenImmunogen: 38C13, murine B cell line Fusion Partners: Spleen cells from immunised Armenian hamsters were fused with cells of the mouse PX3-Ag.8.653 myeloma cell line. Buffer Solution: Phosphate buffered saline Target Species: Mouse
Other Names[CD81 antigen; CD81 antigen; CD81 antigen; 26 kDa cell surface protein TAPA-1; target of the antiproliferative 1; CD81 antigen; 26 kDa cell surface protein TAPA-1; Target of the antiproliferative 1; CD_antigen: CD81], [Cd81; Cd81; Tapa1; Tapa-1; Tspan28; Tapa1]
Gene, Accession #[CD81], Gene ID: 12520, NCBI: NP_598416.1, UniProt: P35762
Catalog #MBS210783
Price$370
Order / More InfoMouse CD81 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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