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Antigenic Specificity | Mouse CD81 |
Clone | [Eat2] |
Host Species | Hamster |
Reactive Species | n/a |
Isotype | IgG1 |
Format | fluorescein (FITC) conjugate |
Size | 0.1 mg |
Concentration | IgG concentration 0.1 mg/ml |
Applications | Flow cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Hamster anti Mouse CD81 antibody, clone Eat2 recognizes mouse and rat CD81, also known as TAPA-1 or Target of the antiproliferative antibody 1. CD81 is a 236 amino acid ~26 kDa multipass transmembrane protein belonging to the TM4SF family (UniProt: P35762). In rodents CD81 is expressed at much higher levels on resting B cells than on T cells, although increased expression on T cells is found following activation. Hamster anti Mouse CD81 antibody, clone Eat2 induces homotypic aggregation of B cells and inhibits anti Ig and IL-4 induced proliferation (Maecker et al. 2000). Eat 2 requires the presence of both extracellular loops of TAPA-1 for binding. Mice lacking CD81 demonstrate reduced fertility through impaired oocyte-sperm fusion, double |
Immunogen | Immunogen: 38C13, murine B cell line Fusion Partners: Spleen cells from immunised Armenian hamsters were fused with cells of the mouse PX3-Ag.8.653 myeloma cell line. Buffer Solution: Phosphate buffered saline Target Species: Mouse |
Other Names | [CD81 antigen; CD81 antigen; CD81 antigen; 26 kDa cell surface protein TAPA-1; target of the antiproliferative 1; CD81 antigen; 26 kDa cell surface protein TAPA-1; Target of the antiproliferative 1; CD_antigen: CD81], [Cd81; Cd81; Tapa1; Tapa-1; Tspan28; Tapa1] |
Gene, Accession # | [CD81], Gene ID: 12520, NCBI: NP_598416.1, UniProt: P35762 |
Catalog # | MBS210783 |
Price | $370 |
Order / More Info | Mouse CD81 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |