MRE11A Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMRE11A
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatantigen affinity purified
Size0.1 mL
Concentration1.9 mg/ml
ApplicationsImmunohistochemistry (IHC)
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DescriptionThe antibody detects endogenous levels of total MRE11A protein. This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two
ImmunogenImmunogen: Synthetic peptide of human MRE11A
Other Names[ATLD; HNGS1; MRE11; MRE11B]
Gene, Accession #[MRE11A], Gene ID: 4361, NCBI: NP_005581.2, UniProt: P49959
Catalog #MBS9415328
Price$255
Order / More InfoMRE11A Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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