Edit |   |
---|---|
Antigenic Specificity | TLR1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: TLR1 antibody detects endogenous levels of total TLR1. Description: Members of the Toll-like receptor (TLR) family, named for the closely related Toll receptor in Drosophila, play a pivotal role in innate immune responses (1-3). TLRs recognize conserved motifs found in various pathogens and mediate defense responses. Triggering of the TLR pathway leads to the activation of NF-kappaB and subsequent regulation of immune and inflammatory genes. The TLRs and members of the IL-1 receptor family share a conserved stretch of approximately 200 amino acids known as the TIR domain. Upon activation, TLRs associate with a number of cytoplasmic adaptor proteins containing TIR domains including MyD88 (myeloid differentiation factor), MAL/TIR |
Immunogen | Immunogen: A synthesized peptide derived from human TLR1 Subcellular Location: Cell Membrane. Cytoplasmic Vesicle > Phagosome Membrane. Tissue Specificity: Ubiquitous. Highly expressed in spleen, ovary, peripheral blood leukocytes, thymus and small intestine. Predicted Cross Reactivity: Bovine, Horse, Rabbit, Dog Similarity: Bovine (80%), Horse (88%), Rabbit (89%), Dog (90%) |
Other Names | [CD281; CD281 antigen; KIAA0012; LPRS5; rsc786; TIL; TIL. LPRS5; Tlr1; TLR1_HUMAN; Toll (Drosophila) homolog; Toll like receptor 1; Toll-like receptor 1; Toll/interleukin-1 receptor-like protein] |
Gene, Accession # | [TLR1], Gene ID: 7096, NCBI: NP_003254.2, UniProt: Q15399 |
Catalog # | MBS9606838 |
Price | $240, $280 |
Order / More Info | TLR1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |